Zhuzhou Yuancheng Tec Ltd

Product name: Domperidone
Trade Name: Motilium
Synonyms: 6-chloro-3- [1- [3- (2-oxo-3H-benzimidazol-1-yl) propyl] piperidin-4-yl] -1H-benzimidazol-2-one;
CAS number: 57808-66-9
Molecular formula: C22H24ClN5O
Molecular weight: 425.91
Purity Assay: Not less than 96% or 99%.
Exact mass: 425.162
PSA: 78.82000
LogP: 3.29110
Appearance:White or almost white crystalline powder, odorless, tasteless
Density: 1.341 g / cm3
Melting point: 242.5ºC
Stability: Stable, incompatible with strong oxidizing agents
Storage conditions: sealed and saved

Security Information
Customs Code: 2933990090
WGK Germany: 3
Hazard Codes: R62; R63
Safety Instructions: S26-S36
RTECS number: DE2275900
Dangerous goods mark: Xn

use
Domperidone is a benzimidazole compound with strong gastric motility and antiemetic effects, can enhance the lower esophageal sphincter tension, prevent gastroesophageal reflux, enhance gastric motility and promote gastric emptying, coordination of the stomach and the fingers Intestinal movement, inhibition of nausea, vomiting, and effectively prevent bile reflux, does not affect gastric secretion. This product is a peripheral dopamine receptor antagonist, a direct block gastrointestinal dopamine receptors appear to promote gastric motility. Can enhance the esophageal motility and lower esophageal sphincter tension. Because of its poor penetration of the blood-brain barrier, it has almost no antagonistic effect on dopamine receptors in the brain and therefore can exclude mental and central nervous side effects